| Bioactivity | MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1]. |
| Target | mGluR2, mGluR 3 |
| Name | MTPG |
| CAS | 169209-66-9 |
| Formula | C10H11N5O2 |
| Molar Mass | 233.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [2]. Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310. |