| Bioactivity | MRV03-069 (Compound 3) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-069 can be used in colorectal cancer research[1]. |
| Target | ClbP. |
| Invitro | MRV03-069 can inhibit colibactin-associated genotoxicity without damaging other members of the gut microbiota[1]. |
| Name | MRV03-069 |
| CAS | 2797066-35-2 |
| Formula | C13H19BN2O4 |
| Molar Mass | 278.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Volpe MR, et al. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat Chem Biol. 2022 Oct 17. |
MRV03-069
CAS: 2797066-35-2 F: C13H19BN2O4 W: 278.11
MRV03-069 (Compound 3) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect o
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