| Bioactivity | MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1]. |
| Target | IC50: < 100 nM (MRGPR X4) |
| Name | MRGPRX4 modulator-2 |
| CAS | 2492595-24-9 |
| Formula | C15H9ClF4O3 |
| Molar Mass | 348.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55) |