| Bioactivity | MR-16728 hydrochloride is a compound that promotes the release of acetylcholine and has activity that enhances the release of acetylcholine. MR-16728 hydrochloride inhibits acetylcholine release induced by KCl depolarization. MR-16728 hydrochloride also inhibits Ca(2+)-ATPase activity in pure presynaptic membranes. The half-maximal effect of MR-16728 hydrochloride occurs at a concentration of 13.5 μM. MR-16728 hydrochloride significantly enhances the release of acetylcholine in the presence of low concentrations of calcium (approximately 10 μM range). Enhanced acetylcholine release was also observed with MR-16728 hydrochloride in proteoliposomes loaded with mediator proteins[1]. |
| CAS | 207403-36-9 |
| Formula | C23H37ClN2O |
| Molar Mass | 393.01 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. The effect of MR16728, a cetiedil analogue, on acetylcholine release in Torpedo synaptosomes |
MR-16728 hydrochloride
CAS: 207403-36-9 F: C23H37ClN2O W: 393.01
MR-16728 hydrochloride is a compound that promotes the release of acetylcholine and has activity that enhances the relea
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