PeptideDB

MPTP hydrochloride

CAS: 23007-85-4 F: C12H16ClN W: 209.72

MPTP hydrochloride is a brain penetrant dopamine neurotoxin, inducing Parkinson’s Disease. MPTP hydrochloride, a precus
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity MPTP hydrochloride is a brain penetrant dopamine neurotoxin, inducing Parkinson’s Disease. MPTP hydrochloride, a precusor of MPP+, induces apoptosis[1][2][3].
Invitro Pretreatment with 50 mM 4-phenylpyridine, reduces IC50 (concentration for 50% inhibition of twitch amplitude) values of MPTP from 53 to 18 mM and d-tubocurarine from 0.7 to 0.3 mM, respectively, in mouse phrenic nerve-diaphragm[2].
Name MPTP hydrochloride
CAS 23007-85-4
Formula C12H16ClN
Molar Mass 209.72
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)