| Bioactivity | MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent[1]. |
| Invitro | 根据 DPPH 和 ABTS•+ 清除测定结果，MPO-IN-6 (compound ADC) 相应的 IC50 值分别为 41.04 μM 和 66.13 μM[1]。在 10 mM 浓度下，MPO-IN-6 (compound ADC) 对 α-葡萄糖苷酶 (α-GD) 具有 35% 的抑制作用，随着浓度的增加，活性增加了 81%[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> MPO-IN-6 相关抗体: |
| Formula | C16H12N2O6 |
| Molar Mass | 328.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Reshma Rajan, et al. Synthesis, Structural Elucidation, In Silico and In Vitro Studies of New Class of Methylenedioxyphenyl-Based Amide Derivatives as Potential Myeloperoxidase Inhibitors for Cardiovascular Protection. ACS Omega. 2024 Feb 7;9(7):7850-7868. |