| Bioactivity | MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1]. |
| Name | MPO-IN-4 |
| CAS | 2088545-68-8 |
| Formula | C12H11N5 |
| Molar Mass | 225.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723. |