| Bioactivity | MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM. | ||||||||||||
| Invitro | MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM. MPI-0479605 (0.1-10 μM) reduces cell viability of HCT-116 cells in a dose-dependent manner. MPI-0479605 shows severe defects in the ability to align chromosomes at the metaphase plate, but causes complete cytokinesis[1]. | ||||||||||||
| Name | MPI-0479605 | ||||||||||||
| CAS | 1246529-32-7 | ||||||||||||
| Formula | C22H29N7O | ||||||||||||
| Molar Mass | 407.51 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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