| Bioactivity | MPCI is a cell-permeant MC4R-selective ligand with pharmacological chaperone activity. MPCI is a MC4R antagonist with a Ki value of 0.218 μM on HEK293 cells expressing hMC4R. MPCI can be used for the research of MC4R-deficient obesity[1]. |
| Target | Ki: 0.218 μM (HEK293 cells expressing hMC4R). |
| Name | MPCI |
| CAS | 884538-31-2 |
| Formula | C25H32BrFN4O2 |
| Molar Mass | 519.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. René P, et al. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity. J Pharmacol Exp Ther. 2010 Dec;335(3):520-32. |