| Bioactivity | MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 (IC50=35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2, and induces K562 cell cycle arrest[1]. | ||||||||||||
| CAS | 708287-29-0 | ||||||||||||
| Formula | C24H25BrF2N4O2S | ||||||||||||
| Molar Mass | 551.45 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Niazi, et al. "Synthesis, characterization, and anti-cancer potential of novel p53-mediated Mdm2 and Pirh2 modulators: an integrated In silico and In vitro approach." Frontiers in Chemistry 12 (2024): 1366370. |
MMs02943764
CAS: 708287-29-0 F: C24H25BrF2N4O2S W: 551.45
MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effec
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