| Bioactivity | MMV688845 is a nontuberculous mycobacteria (NTM) RNA polymerase inhibitor with bactericidal activity against Mycobacterium abscessus and anti-tuberculosis efficacy[1]. | ||||||||||||
| Invitro | MMV688845 可以以剂量依赖的方式抑制M. abscessus ATCC 19977,且其 MIC值为 9.3 μM。 | ||||||||||||
| Name | MMV688845 | ||||||||||||
| CAS | 2208962-35-8 | ||||||||||||
| Formula | C24H25N3O3S | ||||||||||||
| Molar Mass | 435.54 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Jinsun Jeong, et al. Pathogen Box screening for hit identification against Mycobacterium abscessus. PLoS One. 2018 Apr 26;13(4):e0195595. |