| Bioactivity | MMV688533 is an antimalarial agent with rapid anti-plasmodial activity and effective single-dose activity against Plasmodium falciparum infection in humanized mouse models. MMV688533 can inhibit the activity of asexual blood stage parasites with an IC50 value of 1.3 nM. MMV688533 exhibits excellent pharmacokinetic properties and safety[1]. |
| CAS | 2260904-47-8 |
| Formula | C24H15F6N5O2 |
| Molar Mass | 519.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Murithi J M, et al. The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance[J]. Science translational medicine, 2021, 13(603): eabg6013. |
MMV688533
CAS: 2260904-47-8 F: C24H15F6N5O2 W: 519.40
MMV688533 is an antimalarial agent with rapid anti-plasmodial activity and effective single-dose activity against Plasmo
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