| Bioactivity | MMV1634566 is a potent antimalarial agent. MMV1634566 inhibits Plasmodium falciparum. MMV1634566 shows cytotoxicity[1]. |
| Invitro | MMV1634566 (0-40 µM; 48 h) 抑制细胞生长，对 HepG2 细胞的 CC50 值为 4.81 µM[1]。MMV1634566 (72 h) 抑制 Plasmodium falciparum 3D7 寄生虫，EC50 值为 0.016 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> MMV1634566 相关抗体: |
| Formula | C22H25N5O2 |
| Molar Mass | 391.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Calic PPS, et al. Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the P. falciparum transporter ABCI3. Eur J Med Chem. 2024 Jul 14;276:116677. |