Bioactivity | MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 µM. MMV019313 has activity against P. falciparum (Parasite)[1]. |
Invitro | MMV019313 可有效抑制培养的人红细胞中 P. falciparum 的复制,EC50 值为 90 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> MMV019313 相关抗体: |
CAS | 902630-14-2 |
Formula | C22H27N3O2S |
Molar Mass | 397.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kabeche S, et al. Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS. Bioorg Med Chem Lett. 2021 Jun 1;41:127978. |