| Bioactivity | MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM)，involved in osteoarthritis (OA)[1]. |
| Target | IC50: 177 μM (MMP-1), 3.6 μM (MMP-2), 50 μM (MMP-9), 1.8 μM (MMP-13), >200 μM (MMP-14) |
| Name | MMP13-IN-5 |
| Formula | C22H18BrN3O5 |
| Molar Mass | 484.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098. |