Bioactivity | MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1]. |
In Vivo | MMP-8 inhibitor-1 (compound 21) (100 mg/kg,口服)的口服生物利用度不明显,剂量为100mg /kg的最大血浆水平 (Cmax) 仅为2.3 mg/mL[1]。 |
Name | MMP-8 inhibitor-1 |
CAS | 236403-25-1 |
Formula | C17H18N2O5S |
Molar Mass | 362.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Matter H, et al. Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship. Bioorg Med Chem. 2002 Nov;10(11):3529-44. |