| Bioactivity | MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C)[1]. | ||||||
| Invitro | MM 419447 exhibits high-affinity binding to T84 cells, resulting in a significant, concentration-dependent accumulation of intracellular cyclic guanosine-39,59-monophosphate (cGMP)[1]. | ||||||
| Name | MM 419447 | ||||||
| CAS | 1092457-78-7 | ||||||
| Shortening | CCEYCCNPACTGC (Disulfide bridge:Cys1-Cys6; Cys2-Cys10; Cys5-Cys13) | ||||||
| Formula | C50H70N14O19S6 | ||||||
| Molar Mass | 1363.56 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
MM 419447
CAS: 1092457-78-7 F: C50H70N14O19S6 W: 1363.56
MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of t
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