| Bioactivity | MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1]. | ||||||||||||
| Invitro | MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro[1]. | ||||||||||||
| Name | MLK-IN-1 | ||||||||||||
| CAS | 1627729-62-7 | ||||||||||||
| Formula | C23H20N4O3S | ||||||||||||
| Molar Mass | 432.49 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Val S. Goodfellow,et al.Mixed lineage kinase inhibitors and method of treatments. Patent US20140256733A1. |