| Bioactivity | ML345 is a potent and selective insulin-degrading enzyme (IDE) small-molecule inhibitor, with an IC50 value of 188 nM. ML345 can be for use as a pharmacophore for drug development in diabetes research[1]. |
| Target | IC50: 188 nM (IDE) |
| Name | ML345 |
| CAS | 1632125-79-1 |
| Formula | C21H22FN3O5S2 |
| Molar Mass | 479.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bannister TD, et al. ML345, A Small-Molecule Inhibitor of the Insulin-Degrading Enzyme (IDE). In: Probe Reports from the NIH Molecular Libraries Program. Bethesda (MD): National Center for Biotechnology Information (US); December 17, 2012. |
ML345
CAS: 1632125-79-1 F: C21H22FN3O5S2 W: 479.54
ML345 is a potent and selective insulin-degrading enzyme (IDE) small-molecule inhibitor, with an IC50 value of 188 nM. M
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