| Bioactivity | ML267 a potent Sfp phosphopantetheinyl transferase (PPTases) inhibitor with an IC50 of 0.29 μM. ML267 also inhibits AcpS-PPTase with an IC50 of 8.1 μM. ML267 possesses specific Gram-positive-targeted bactericidal activities[1]. |
| Target | IC50: 0.29 μM (Sfp-PPTases) and 8.1 μM (AcpS-PPTase) |
| Name | ML267 |
| CAS | 1542213-67-1 |
| Formula | C19H18ClF6N5O3S |
| Molar Mass | 545.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Foley TL, et al. J. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. J Med Chem. 2014 Feb 13;57(3):1063-78. |
ML267
CAS: 1542213-67-1 F: C19H18ClF6N5O3S W: 545.89
ML267 a potent Sfp phosphopantetheinyl transferase (PPTases) inhibitor with an IC50 of 0.29 μM. ML267 also inhibits Acp
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.