| Bioactivity | ML-191 is an antagonist of GPR55. It inhibits GPR55 signaling induced by lysophosphatidylinositol (EC50=1.076 µM in U2OS cells overexpressing GPR55). ML-191 inhibits LPI-induced phosphorylation of ERK1/2 (IC50=328 nM) and receptor-dependent translocation of PKCβII when used at a concentration of 30 µM[1]. |
| Name | ML191 |
| CAS | 931695-79-3 |
| Formula | C24H25N3O3 |
| Molar Mass | 403.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Heynen-Genel S, et al. Screening for Selective Ligands for GPR55 - Antagonists. 2010 Oct 30 |