| Bioactivity | MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family[1][2][3]. | ||||||||||||
| Name | MKC-1 | ||||||||||||
| CAS | 125313-92-0 | ||||||||||||
| Formula | C22H16N4O4 | ||||||||||||
| Molar Mass | 400.39 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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