| Bioactivity | MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome[1][2]. |
| In Vivo | MK771 (5 mg/kg；腹腔注射) 诱导小鼠眨眼和前爪舔[1]。MK771 (10 ng-10 µg/小鼠；i.c.v.) 在小鼠体内产生高热反应[2]。 Animal Model: |
| Name | MK771 |
| CAS | 66537-55-1 |
| Formula | C16H22N6O4S |
| Molar Mass | 394.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. McCreary AC, et al. The thyrotrophin-releasing hormone analogue MK771 induces tic-like behaviours: the effects of dopamine D1 and D2 receptor antagonists. Eur J Pharmacol. 1999 Mar 12;369(1):1-9. [2]. Bhargava HN, et al. Comparative effects of thyrotropin releasing hormone, MK-771 and DN-1417 on morphine abstinence syndrome. Psychopharmacology (Berl). 1985;87(2):141-6. |