Bioactivity | MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs), exhibiting high specificity and selectivity for binding to NFTs[1]. | ||||||||||||
Target | Ki: NFT. | ||||||||||||
CAS | 1841078-87-2 | ||||||||||||
Formula | C16H11FN4 | ||||||||||||
Molar Mass | 278.28 | ||||||||||||
Appearance | 固体 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Walji AM, et al. Discovery of 6-(Fluoro-(18)F)-3- (1H-pyrrolo [2,3-c]pyridin-1-yl) isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs). J Med Chem. 2016 May 26;59(10):4778-89. |