| Bioactivity | MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI). MK-4965 displays excellent activities against not only HIV-1 wild-type (WT) virus but also against a broad panel of NNRTI-resistant viruses and can be used for the research of HIV-1 infection[1]. |
| Target | IC50: 0.23 nM (WT), 0.39 nM (Y181C), 0.40 nM (K103N) |
| Name | MK-4965 |
| CAS | 920035-77-4 |
| Formula | C20H13Cl2N5O2 |
| Molar Mass | 426.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lai MT, et al. Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2009 Jun;53(6):2424-31. |
MK-4965
CAS: 920035-77-4 F: C20H13Cl2N5O2 W: 426.26
MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI). MK-4965 displays excellent activities against not on
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