Bioactivity | MK-4882 is an HCV NS5A inhibitor with activity in reducing viral load in a chimpanzee model of HCV infection, but with issues of viral breakthrough, prompting the development of compounds with greater potency against more genotypes and NS5A resistance mutations. |
CAS | 1246470-32-5 |
Formula | C42H50N8O7 |
Molar Mass | 778.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Discovery of potent macrocyclic HCV NS5A inhibitors [2]. Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity [3]. Discovery and development of hepatitis C virus NS5A replication complex inhibitors |