| Bioactivity | MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1]. |
| Name | MK-1468 |
| CAS | 2769107-89-1 |
| Formula | C26H33ClN4O4 |
| Molar Mass | 501.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kattar SD, et al. Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease. J Med Chem. 2023 Oct 20. |
MK-1468
CAS: 2769107-89-1 F: C26H33ClN4O4 W: 501.02
MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study
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