| Bioactivity | MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1]. |
| Target | IC50: 1.4 μM (MIF)Ki: 0.96 μM (MIF) |
| Name | MIF-IN-6 |
| CAS | 2582758-61-8 |
| Formula | C18H13ClFN5O2 |
| Molar Mass | 385.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849. |
MIF-IN-6
CAS: 2582758-61-8 F: C18H13ClFN5O2 W: 385.78
MIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a
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