| Bioactivity | MI-888 is an orally active MDM2 inhibitor with a Ki of 0.44 nM. MI-888 can inhibit the MDM2-p53 interaction. MI-888 has favorable pharmacokinetic properties and anti-tumor activity[1]. |
| CAS | 1303607-59-1 |
| Formula | C28H32Cl2FN3O3 |
| Molar Mass | 548.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhao Y, et al. A potent small-molecule inhibitor of the MDM2-p53 interaction (MI-888) achieved complete and durable tumor regression in mice. J Med Chem. 2013 Jul 11;56(13):5553-61. |
MI-888
CAS: 1303607-59-1 F: C28H32Cl2FN3O3 W: 548.48
MI-888 is an orally active MDM2 inhibitor with a Ki of 0.44 nM. MI-888 can inhibit the MDM2-p53 interaction. MI-888 has
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