| Bioactivity | MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. Anticaner and neuroprotective activities[1][2]. | |||||||||
| Invitro | MI-192 (0.15-1 μM; 72 h) induces differentiation and is cytotoxic through promotion of apoptosis in acute myeloid leukaemic cell lines U937, HL60 and Kasumi-1[1]. Apoptosis Analysis[1] Cell Line: | |||||||||
| Name | MI-192 | |||||||||
| CAS | 1415340-63-4 | |||||||||
| Formula | C24H21N3O2 | |||||||||
| Molar Mass | 383.44 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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