| Bioactivity | MHY 553 is an oral PPARα agonist that alleviates liver steatosis by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY553 inhibits triglyceride accumulation induced by liver X receptor agonists in HepG2 cells. MHY553 significantly suppresses inflammatory mRNA expression in aged rats[1]. |
| CAS | 6265-56-1 |
| Formula | C13H9NO2S |
| Molar Mass | 243.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Seong Min Kim, et al. Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget. 2017 May 8;8(28):46273–46285. |