| Bioactivity | MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity[1]. | ||||||||||||
| Invitro | MHP (50-250 μM for 24 hours) increases CAMP mRNA levels in keratinocytes[1].MHP (100 μM for 24 hours) increases CAMP protein levels in keratinocytes[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | MHP | ||||||||||||
| CAS | 1104874-94-3 | ||||||||||||
| Formula | C16H23NO4 | ||||||||||||
| Molar Mass | 293.36 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34. |