| Bioactivity | MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1]. | ||||||||||||
| Target | IC50:121 nM (VISTA ) | ||||||||||||
| CAS | 920157-23-9 | ||||||||||||
| Formula | C20H17F2N3O2 | ||||||||||||
| Molar Mass | 369.37 | ||||||||||||
| Appearance | 粉末 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Abdel-Rahman SA, et al. Small molecules from antibody pharmacophores (SMAbPs) as a hit identification workflow for immune checkpoints. Sci Adv. 2024 Oct 18;10(42):eadq5540. |
MG-V-53
CAS: 920157-23-9 F: C20H17F2N3O2 W: 369.37
MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 valu
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