| Bioactivity | MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1]. | ||||||||||||
| Invitro | MG-101 (0-26 μM; 24 h) affects the growth of colon cancer HCT116 cells[1].MG-101 (0-26 μM; 24 h) induces apoptosis of various cancer cells[1].MG-101 (0-26 μM; 24 h) induces Bax-dependent apoptosis in HCT116 cells[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | MG-101 | ||||||||||||
| CAS | 110044-82-1 | ||||||||||||
| Formula | C20H37N3O4 | ||||||||||||
| Molar Mass | 383.53 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|