| Bioactivity | MFZ 10-7 is a potent mGluR5 antagonist. Intraperitoneal administration of MFZ 10-7 inhibits intravenous cocaine self-administration, cocaine-induced reinstatement of drug-seeking behavior and cocaine-associated cue-induced cocaine-seeking behavior in rats[1].. | ||||||||||||
| Target | mGluR5 | ||||||||||||
| Name | MFZ 10-7 | ||||||||||||
| CAS | 1224431-15-5 | ||||||||||||
| Formula | C15H9FN2 | ||||||||||||
| Molar Mass | 236.24 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Keck TM, et al. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addict Biol. |