| Bioactivity | METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research[1]. |
| Target | METTL3 |
| Name | METTL3-IN-5 |
| CAS | 2965311-25-3 |
| Formula | C23H22FN5O2S |
| Molar Mass | 451.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhong Chen, et al. Mettl3 inhibitor and composition, and application of same in medicine. WO2023151697 A1. |