Bioactivity | METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research[1]. |
Target | METTL3 |
Name | METTL3-IN-5 |
CAS | 2965311-25-3 |
Formula | C23H22FN5O2S |
Molar Mass | 451.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhong Chen, et al. Mettl3 inhibitor and composition, and application of same in medicine. WO2023151697 A1. |