| Bioactivity | METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor[1]. |
| Target | METTL3 |
| Invitro | METTL3，即 N6 -腺苷甲基转移酶 70 kDa 亚基，是 MT-A 的 70 kDa 亚基。MT-A 是 N6 -腺苷甲基转移酶的一部分。METTL3 参与真核 mRNA 内部腺苷残基的转录后甲基化，形成 N6 -甲基腺苷 (m6A)[2]。 |
| Name | METTL3-IN-1 |
| CAS | 2648257-77-4 |
| Formula | C25H24FN5O2 |
| Molar Mass | 445.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Blackaby WP, et al. Preparation of polyheterocyclic compounds as METTL3 inhibitors: World Intellectual Property Organization, WO2021111124[P]. 2021-06-10. [2]. METTL3, Wikipedia. |