| Bioactivity | MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids[1]. |
| Formula | C17H26N2O |
| Molar Mass | 274.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Z. CHAHINE, et al. A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science. 2024 Sep 27;385(6716):eadm7966. |