PeptideDB

MDTF

CAS: F: C16H10F4NNaO9S W: 491.30

MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Invitro MDTF (50 μM) increases hydrophilic character by substitution of a cyclohexyl ring and a MD-based FRET probe incubates in human plasma has a considerably higher self-stabilization rate compared to the MCC-based probe[1].
Name MDTF
Formula C16H10F4NNaO9S
Molar Mass 491.30
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month