Bioactivity | MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1]. |
Invitro | Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1]. |
Name | MCC |
CAS | 104676-09-7 |
Formula | C12H16N2O3 |
Molar Mass | 236.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |