| Bioactivity | MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain permeability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice[1]. | ||||||||||||
| Name | MCAAD-3 | ||||||||||||
| CAS | 1625629-51-7 | ||||||||||||
| Formula | C17H18N2O2 | ||||||||||||
| Molar Mass | 282.34 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Fu H, et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem Commun (Camb). 2014 Oct 14;50(80):11875-8. |