| Bioactivity | MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway[1]. |
| Invitro | MC2646 (4 µM; 24 h) 通过增加 LC3-II:LC3-I 比率来诱导自噬通量[1]。MC2646 (4 µM; 24 h) 可增加 p-AMPK 的表达并增加细胞核:细胞质的 TFEB 定位[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> MC2646 相关抗体: Western Blot Analysis[1] Cell Line: |
| Formula | C21H20N2O |
| Molar Mass | 316.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Villares M, et al. Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy. Nat Commun. 2024 Mar 12;15(1):2235. |