| Bioactivity | MC-SN38 is a drug-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody drug conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. | |||||||||
| Name | MC-SN38 | |||||||||
| CAS | 1473403-87-0 | |||||||||
| Formula | C32H31N3O8 | |||||||||
| Molar Mass | 585.60 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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