PeptideDB

MBP Ac1-9 (4Y)

CAS: 167278-49-1 F: C47H75N17O16 W: 1134.20

MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific
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Bioactivity MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis[1].
CAS 167278-49-1
Sequence Ac-Ala-Ser-Gln-Tyr-Arg-Pro-Ser-Gln-Arg
Shortening Ac-ASQYRPSQR
Formula C47H75N17O16
Molar Mass 1134.20
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Huang J C, et al. T cell recognition of distinct peptide: I-Au conformers in murine experimental autoimmune encephalomyelitis[J]. The Journal of Immunology, 2003, 171(5): 2467-2477.