| Bioactivity | MAT2A inhibitor 5(compound 39) is an orally active, selectivity and blood-brain permeability inhibitor of MAT2A with the IC50 of 11 nM. MAT2A inhibitor 5 inhibits tumor cell growth in vivo[1]. |
| CAS | 2957874-18-7 |
| Formula | C19H14ClFN4O |
| Molar Mass | 368.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Faridoon, et al. Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy. J Med Chem. 2024;67(11):9431-9446. |
MAT2A inhibitor 5
CAS: 2957874-18-7 F: C19H14ClFN4O W: 368.79
MAT2A inhibitor 5(compound 39) is an orally active, selectivity and blood-brain permeability inhibitor of MAT2A with the
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