Bioactivity | MAT2A-IN-20 (Compound A49) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 ≤50 nM. MAT2A-IN-20 inhibits human UGT1A1 with an IC50 of 28.45 μM. MAT2A-IN-20 exhibits antitumor in mouse models[1]. |
CAS | 3018834-98-2 |
Formula | C26H24F2N6O4 |
Molar Mass | 522.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang K, et al., Pyrimido nitrogen-containing six-membered aromatic heterocyclic compound and application thereof. CN115504980A. |