Bioactivity | MART-1 (26-35) (human) is amino acid residue 26 to 35 of MART-1 protein. |
Invitro | MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes[1]. In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26–35 and 27–35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses[2]. |
Name | MART-1 (26-35) (human) |
CAS | 156251-01-3 |
Sequence | Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val |
Shortening | EAAGIGILTV |
Formula | C42H74N10O14 |
Molar Mass | 943.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |