PeptideDB

MAO-B-IN-27

CAS: 788824-83-9 F: C16H17ClF3NO W: 331.76

MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibi
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Bioactivity MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1].
Target IC50: 8.9 nM (hMAO-B).
Name MAO-B-IN-27
CAS 788824-83-9
Formula C16H17ClF3NO
Molar Mass 331.76
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26(1):232-244.