| Bioactivity | MAO-B-IN-27 (Compound 12c) is a monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-27 has potent and selective MAO-B inhibitory effect for hMAO-B with an IC50 values of 8.9 nM. MAO-B-IN-27 can be used for the research of parkinson's disease (PD)[1]. |
| Target | IC50: 8.9 nM (hMAO-B). |
| Name | MAO-B-IN-27 |
| CAS | 788824-83-9 |
| Formula | C16H17ClF3NO |
| Molar Mass | 331.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yeon SK, et al. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy. Bioorg Med Chem. 2018 Jan 1;26(1):232-244. |