| Bioactivity | MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B (IC50: 1.60 μM). MAO-B-IN-24 also inhibited MAO-A (22.42 μM); at 10 μM concentration, it also reduced AChE and BChE activities to 54.58% and 88.43%[1]. |
| Target | IC50: 1.60 μM (human MAO-B), 22.42 μM (human MAO-A) |
| Name | MAO-B-IN-24 |
| Formula | C20H18N2O |
| Molar Mass | 302.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Perumal K, et al. An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. RSC Adv. 2023 Aug 22;13(36):24925-24935.. . |