| Bioactivity | MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1]. |
| Invitro | MAO-B-IN-15 (Compound 4i, 0.01-1000 μM, 1 h) dose-dependently inhibits MAO-B activity[1].MAO-B-IN-15 (10 μM, 24 h) has no effect on cell viability of SH-SY5Y cells[1]. |
| Name | MAO-B-IN-15 |
| CAS | 2032436-79-4 |
| Formula | C17H18FNO2 |
| Molar Mass | 287.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. https://doi.org/10.1021/acsmedchemlett.2c00228. |
MAO-B-IN-15
CAS: 2032436-79-4 F: C17H18FNO2 W: 287.33
MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-
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